Central Serous Chorioretinopathy Causes:

Known causes of this condition are nicely summarized here. It is quite common for a person to be taking medication which, while extremely rare, can contribute to causing CSR. Click here for an article summarizing potential contributing factors.

Don’t overlook occasionally used drugs, supplements or homeopathic nutraceuticals. For example, pseudoephedrine in an over the counter allergy medication was causing CSR in a patient.

Research on treatment:

Central Serous Chorioretinopathy is generally a self-resolving condition. If it does not go away on its own (or reoccurs), there seems to be a novel treatment that has worked extremely well at the case study level. Large, controlled studies have not yet been completed (at time of writing).  However, you can read about a ground breaking French study by clicking here.

Potential treatment for chronic/reoccurring CSR:

Spironolactone and Eplerenone are two prescriptions drugs belong is a drug category called aldosterone antagonists.

Eplerenone has been used anecdotally to treat chronic CSR – and with rather astounding effect in some patients. Below is an optical coherence tomograph of a patients macula showing before and after
5 weeks of Eplerenone treatment.

The top picture is prior to treatment and the bottom picture is after 1 week (25 mg) followed by 4 weeks (50 mg) (5 weeks total) treatment with Eplerenone. Yes, that is the same eye only 5 weeks apart!

The top picture is prior to treatment and the bottom picture is after 1 week (25 mg) followed by 4 weeks (50 mg) (5 weeks total) treatment with Eplerenone. Yes, that is the same eye only 5 weeks apart!

The patient reported a daily, noticeable improvement starting on day 3 of the Eplerenone treatment
culminating in no noticeable distortions in their Amsler grid.

The patient in this picture started Eplerenone on December 3, 2012 and has not had a relapse or any
fluid since. In the French study above, the patients were followed for 5 months without reoccurrence.

Conclusion:

Please feel free to print this page and the documents within it and give it to your Primary and Eye
Doctors. Please contact us with any results you have and we’ll add them to this page. If you have information to share, please contact us as well.

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